Solvent interactions in E-DNA. The deep major groove and shallow minor groove, along with the relatively noninclined base pairs result in a more exposed surface for E-DNA.

Figure 2: Sequence-specific interactions between the rhodium complex and the DNA major groove. a, Space-filling model of the binding site. The C5A, C5, ...

This DNA tetrahedron is the smallest 3D nanostructure made by DNA self-assembly. Comparison between the 3D density map and structural models of the two expected diastereomers. (a,b) Space-filling ...

A number of methods have been deployed to overcome this, all the methods aiming at functionalizing the mica to develop a positive interface to which DNA can attach. In the year 2012, Leung et al. were ...

New study finds that DNA molecules directly interact with one another in a way that's dependent on the sequence of the DNA and epigenetic factors. ... relocating spermine from major grooves to ...

Such an evolutionary order makes sense, Porter says, because the helix-turn-helix binds only to the major groove of DNA, whereas the winged helix binds to both the major groove and the minor groove.