In the context of atherosclerosis, TREM2 signaling promotes foam cell formation and is crucial for maintaining macrophage survival and plaque stability through efferocytosis and cholesterol efflux.

Macrophages play a central role in initiating, maintaining, and terminating inflammation. For that, macrophages respond to various external stimuli in changing environments through signaling pathways ...

This study provides useful information by identifying the cell type (macrophages) in synovial tissues involved in the pathogenesis of post-traumatic osteoarthritis (OA) and clarifying distinct ...

The Research Institute for Fragrance Materials (RIFM) congratulates Safety Assessment Team Researcher Marissa Guttenberg, PhD, on receiving the Society of Toxicology (SOT) 2025 Best Paper of the Year ...

Males with pulmonary arterial hypertension (PAH) have more proinflammatory macrophages — a type of immune cell — in the lungs than do females with the disease, a study suggests. Researchers identified ...

如果是，它又是通过什么机制来影响的呢？为了弄清楚这些问题，解放军总医院的研究人员展开了深入的探索，并在《Cell Communication and Signaling》期刊上发表了题为 “Neutrophil extracellular traps impair macrophage efferocytosis via the PI3K/Rac1 pathway in diabetic ...

When exposed to various stimuli, monocytes/macrophages are recruited to and retained within the local tissue microenvironment, where they can activate and display either proinflammatory or ...

No Derivatives (ND): Derivative works may be created for non-commercial purposes, but sharing is prohibited. This study aimed to evaluate iodinated nanoparticles based on Visipaque for the detection ...