芦荟大黄素(Aloe-emodin)这种蒽醌类衍生物展现出令人惊喜的抗癌特性。在人类肝癌细胞系Hep3B中，它像精准的"分子开关"般激活AMP活化蛋白激酶(AMPK)，引发一系列连锁反应：先是促使微管相关蛋白轻链3(LC3-II)和p62从细胞质"搬家"到线粒体，接着显著提升线粒体内PTEN诱导激酶1(PINK1)和parkin的表达水平 ...

HCV infection has been shown to influence mitophagy. Kim et al. reported that HCV-infected cells exhibit a higher number of mitophagosomes compared to uninfected cells. The presence of HCV-induced ...