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Researchers identify key driver of fibrosis in Crohn's diseaseHIF-1α+ macrophages were, in fact, highly abundant in sites of inflammation-associated intestinal fibrosis, but could not be found elsewhere in nearby regions of the intestine.
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Microscopy approach offers new way to study cancer therapeutics at single-cell levelThey found that radiation treatment caused significant metabolic changes in the cells, particularly through the activation of a protein called HIF-1α, which helps cells adapt to low oxygen levels ...
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