Yulan Xiong, associate professor of neuroscience at UConn Health, and her team have discovered one more piece of the puzzle of the genetic causes of Parkinson's Disease, paving the way for new ...

Quantum computing and artificial intelligence (AI) can be combined with classical computing methods to design and discover small-molecule candidates that target the cancer-driving KRAS protein, ...

According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP) and cycle between its active (GTP-bound) and inactive (guanosine diphosphate [GDP]–bound) states ...

Yulan Xiong and her team have discovered a much-searched-for regulator that plays a key role in genetic causes of Parkinson's ...

This knowledge could help foster new treatment initiatives in this challenging context. The RAS (rat sarcoma viral oncogene) protein is a small guanosine triphosphate hydrolase (GTPase) that ...

Glioblastoma, the most common malignant tumor in the brain, lacks effective treatments and is currently incurable. To identify novel drug targets for this deadly cancer, the publicly available results ...

Celery, a key vegetable in the Apiaceae family, is widely valued for its nutrition and medicinal uses. It is commonly categorized into three varieties: A. graveolens var. dulce (common celery ...

State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 430061, PR China ...

Correspondence to Shirley Sze, Department of Cardiovascular Sciences and NIHR Biomedical Research Centre, University of Leicester, Leicester LE3 9QP, UK; shirley.sze{at}nhs.net While progress has been ...