Female RA and LMAN specialized modules were less dependent on estrogen. The estrogen-induced gene modules in females were enriched for anatomical development functions and strongly correlated to the ...

Transposons, or "jumping genes"—DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of antibiotic resistance. Cornell ...

For one, inserting at the end of the chromosome helps the transposon avoid genes for the cell's core functioning, which reside in the middle of the chromosomes; transposons that can target the ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems ...

which occurs in a large circular segment of DNA that exists outside of any chromosome. Although glyphosate resistance had been linked to this odd structure previously, the study provided new insights ...

Mar. 14, 2025 — Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 ...

This work has also created a kind of "treasure map" that investigators can use to fill in the gaps in our knowledge. | ...

Background: Chromosome 15q11–13 contains a cluster of imprinted genes essential for normal mammalian neurodevelopment. Deficiencies in paternal or maternal 15q11–13 alleles result in Prader–Willi or ...

A proof-of-concept study shows that CRISPR-Cas9 can eliminate extra chromosome copies in Down syndrome cells. The method restores normal gene function but is not yet ready for human trials. Scientists ...

For one, inserting at the end of the chromosome helps the transposon avoid genes for the cell's core functioning, which reside in the middle of the chromosomes; transposons that can target the ends ...