Yulan Xiong, associate professor of neuroscience at UConn Health, and her team have discovered one more piece of the puzzle of the genetic causes of Parkinson's Disease, paving the way for new ...

Quantum computing and artificial intelligence (AI) can be combined with classical computing methods to design and discover small-molecule candidates that target the cancer-driving KRAS protein, ...

According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP) and cycle between its active (GTP-bound) and inactive (guanosine diphosphate [GDP]–bound) states ...

Yulan Xiong and her team have discovered a much-searched-for regulator that plays a key role in genetic causes of Parkinson's ...

GTPase: A family of enzymes that hydrolyze guanosine triphosphate (GTP) and are involved in various cellular processes, including signal transduction and protein synthesis. Autophagy: A cellular ...

This knowledge could help foster new treatment initiatives in this challenging context. The RAS (rat sarcoma viral oncogene) protein is a small guanosine triphosphate hydrolase (GTPase) that ...

Within IMSA’s GTP class, cars built to LMDh rules are fielded by Acura, BMW, Cadillac, Lamborghini, and Porsche, and by Alpine, BMW, Cadillac, and Porsche in the WEC’s Hypercar category. Hyundai’s ...

Alzheimer’s disease (AD) is the most common neurodegenerative disorder with the majority of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved. Though sAD is argued ...

State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 430061, PR China ...

“We’re thrilled to continue our long-standing relationship with Cadillac and Action Express Racing in the IMSA GTP class,” said Sonny Whelen, Executive Vice President of Whelen Engineering.