Some pathways may first traffic to intermediate compartments, such as the caveosome or glycosyl phosphatidylinositol-anchored protein-enriched early endosomal compartments (GEEC), en route to the ...

Central to the function of the MVB pathway for trafficking to lysosomes are the endosomal sorting complex required for transport-0 (ESCRT-0), -I, -II and –III complexes, which are represented in ...