Central to the function of the MVB pathway for trafficking to lysosomes are the endosomal sorting complex required for transport-0 (ESCRT-0), -I, -II and –III complexes, which are represented in ...

In a ceremony held last month, the 2024 Louisa Gross Horwitz Prize was awarded to Wesley Sundquist, PhD, Leo T. and Barbara K ...

1D). Thus, the disruption of either the Retromer or Commander-dependent endosomal retrieval pathways does not impair the viability or proliferation of these cells. Together, these global genetic ...

Within these compartments, further invagination of the endosomal membrane occurs, encapsulating cytoplasmic contents such ... with some exhibiting unique or predominant biogenetic pathways. This ...

Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals. Existing ...

TTUHSC student researchers recently participated in the university’s 37th Student Research Week, organized by the TTUHSC Graduate School of Biomedical Sciences. The event allows TTUHSC students to ...

In a recent study published in the journal Genes, our team has identified and characterized 10 sodium/hydrogen antiporter ...

The intracellular barriers include endosomal escape ... a base When asked about the progress Liberate has made on this pathway, Scully stated that the company has focused primarily on building ...