ERRα 促进 PCSCs 向 OXPHOS 的能量代谢转变：利用 Seahorse Extracellular Flux 分析仪检测发现，PCSCs 富集的前列腺球体相对于其贴壁亲本细胞，具有更高的氧消耗率（OCR）和 ATP 产生，同时细胞外酸化率（ECAR）降低，表明 PCSCs 更依赖 OXPHOS 供能。此外，ERRα 过表达增强了 ...

Unlike normal stem cells, which rely heavily on oxidative phosphorylation (OXPHOS) as their primary source of energy, or cancer cells, which are primarily glycolytic, CSCs demonstrate a unique ...

The increased demand for energy also requires a higher metabolic rate of nutrients. In non-malignant cells, this is usually achieved through elevating mitochondrial oxidative phosphorylation (OXPHOS), ...

Processes such as mitochondrial fission, fusion, mitophagy, changes in membrane potential, reactive oxygen species (ROS) accumulation, and oxidative phosphorylation (OXPHOS) are all linked to drug ...

Sam's story 56-year-old Sam was diagnosed with Perrault syndrome when she was 28 years old, after being under the care of various hospitals to diagnose her rare genetic condition. Sam is ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...

Different terms are regularly used in theories of sexuality and gender, for example sex, gender, gender identity, gender expressions, gender roles, sexual orientation. It is important to be clear ...