Cancer Discovery publishes high-impact articles featuring major advances in research and clinical trials. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic to ...

Cells with mutations that allow them to grow uncontrollably and continue to divide without stopping. They are able to invade nearby tissues and spread throughout the body, often evading the immune ...

Whalen, PhD, poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells. Published in Nature Cancer, their work illustrates how a small DNA nick-a break ...

Centre for 3D models of Health and Disease, Division of Surgery and Interventional Science, University College London, London W1W 7TY, U.K. Centre for 3D models of Health and Disease, Division of ...

SUGAR LAND, Texas--(BUSINESS WIRE)--FDA has authorized Hope Biosciences’ adipose-derived mesenchymal stem cells (HB-adMSCs) for use in the first pediatric clinical trial, to evaluate if ...

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Using single-cell ... stem cells. Later in the healing process, the organoids regulated the integrin α5β1-FAK pathway, reducing the transition of fibroblasts to myofibroblasts and remodeling the ...

It's thought that even though cancer appears to be "gone," some cancer cells may remain after treatment in a state of dormancy (cancer stem cells,) which persist until conditions are right for the ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

Cancer stem cells, which act like fugitives, escape immune surveillance and repair mechanisms, lying dormant until the right moment to strike again. “Cancer can develop when genetic disruptions ...