Leukemia - Absence of mutations in the deoxycytidine kinase ... deoxycytidine monophosphate (dCMP) kinase and nucleoside diphosphate (NDP) kinase. Ara-CTP inhibits DNA polymerase, ...

The idea is that molecules such as deoxythymidine monophosphate and deoxycytidine monophosphate would be converted to those required for the synthesis of mitochondrial DNA.

Again, dFdCTP suppresses inactivation of dFdCMP by inhibiting deoxycytidine monophosphate deaminase (DCTD). On the other hand, more than 90% of administered gemcitabine is converted, ...