To pinpoint the location of methyl groups, Ecker and his colleagues process DNA in a way that converts every unmethylated cytosine to a different nucleic acid, uracil. Then, they sequence the DNA in ...

In RNA, a point mutation can involve the substitution of uracil with another nucleobase, such as cytosine (C) or guanine (G). These mutations can potentially alter the amino acid sequence of the ...

How can just four nitrogenous bases--adenine, cytosine, guanine, and uracil--possibly code for all 20 amino acids? Thus, early researchers quickly determined that the smallest combination of As ...

In addition to the five nitrogenous bases—adenine, guanine, cytosine, thymine and uracil—required for building DNA and RNA, the researchers also found xanthine, hypoxanthine, and nicotinic ...

In 1992, researchers found that the amination reaction of sodium bisulfite with unmethylated cytosine is different than the reaction of sodium bisulfite with 5mC. Because of this difference, ...

Nucleotides are the combination of a five-carbon sugar, ribose, along with a phosphate group and one of five possible ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...