Cytochrome P450 enzymes are a crucial family of enzymes ... Recent research has focused on understanding the mechanisms and dynamics of these enzymes, particularly the CYP3A4 and CYP3A5 isoforms ...

Metoprolol is used for phenotyping of cytochrome P450 (CYP) 2D6, a CYP isoform considered not to be inducible by inducers of the CYP2C, CYP2B, and CYP3A families such as rifampicin. While assessing ...

Recent research has focused on understanding the mechanisms behind this resistance ... researchers discovered that overexpression of specific cytochrome P450 enzymes and UDP ...

School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China ...

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China University of Chinese Academy of Sciences, Beijing 100049, China State Key ...

The cytochrome P450 family of enzymes, which are encoded by the CYP genes, help to maintain body homeostasis by metabolizing endogenous hormones and their biochemical intermediates. As such ...

increasing blood pressure through increasing sodium reabsorption and probably other mechanisms. The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved ...

Several fleshy fruits are highly affected by cracking, a severe physiological disorder that compromises their quality and causes high economical losses to the producers. Cracking can occur due to ...

A growing body of evidence links use of proton pump inhibitors to kidney problems, including kidney failure in patients with existing CKD.

Once confined to the province of abstract theory, quantum computing seeks to use operations based on quantum mechanics to ...

Grapefruit juice: To break down some prescription drugs in the body, the liver uses enzymes called cytochrome P450. But grapefruit ... juice through the same mechanism. Increased statin levels ...

Defense mechanisms are rooted in Freud’s theory of personality.According to his model, the mind has three dueling forces: the id (unconscious and primitive urges for food, comfort, and sex), the ...