The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...
Australian researchers have identified a surprising mechanism focusing on telomeres -- protective caps at the ends of ...
Researchers have identified a surprising mechanism that helps cells defend against cancer, a new study by the Sydney-based ...
With age, telomeres -- protective caps at the ends of chromosomes -- naturally shorten, signaling ageing cells to stop ...
Sydney, March 17 (IANS): Australian researchers have identified a surprising mechanism focusing on telomeres -- protective ...
Researchers have identified a surprising mechanism that helps cells defend against cancer, a new study by the Sydney-based Children's Medical Research Institute (CMRI) said on Monday. Telomeres, the ...
Haspin phosphorylates histone H3 threonine 3 (H3T3) to ensure proper progression through mitosis. Here the authors describe how Haspin engages a nucleosomal DNA supergroove, using electrostatic ...
Count Me In, a patient-partnered research initiative led by the Broad Institute of MIT and Harvard and Dana-Farber Cancer ...
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
Abstract Rare and common genetic variants contribute to the risk of atrial fibrillation (AF). Although ion channels were among the first AF candidate genes identified, rare loss-of-function variants ...
Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems ...