Objective We aimed to investigate the role of GPR171 in modulating CD4 + T cell effector functions in IBD and evaluate its therapeutic potential. Conclusions GPR171 deficiency promotes Th17 cell ...

Institute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Bavaria 85764, Germany Chair of Biological Imaging, Central Institute for Translational Cancer Research (TranslaTUM) ...

CD34 and CD45 expression were analyzed via flow cytometry ... cell differentiation. Image Credit: ACROBiosystems NK cells were co-cultured with cells derived with K562. This was done at E:T ...

Scientists prepare samples as single cell suspensions and labels components of interest with fluorescent antibodies or other probes. The cytometer uses pumps to draw the sample through tubing to ...

Adding the TCRA or TCRB 3' UTR to an anti-CD19 chimeric antigen receptor (CAR) improves the ability of the corresponding CAR-T cells to kill tumor cells in vitro. Here, we identified mRNAs that ...

Characterization and isolation of a large population of cells are indispensable procedures in biological sciences. Flow cytometry is one of the standards that offers a method to characterize and ...

Absolute numbers and distribution of B cell subsets were analyzed ex vivo using flow cytometry. Additionally ... Since CD40L and IL-21 are costimulatory molecules usually expressed on CD4+ T cells in ...

BMP4 is a member of the BMP family and is of special interest due to its well-studied osteoinductive properties. Here, we showed the effects of BMP4 on the activation and differentiation of CD4+ T ...