Objectives To study non-metabolic effects of insulin in CD4+ T cells of RA patients. Results In total, 102 new cases of DM were registered, significantly less often in RA patients compared to gout ...

but also direct action of IL-1 on both CD4 + and CD8 + T cells, either alone or in synergy with prototypical polarizing cytokines, influences T cell differentiation under different conditions. The ...

Table 1. Compilation of the different progenitors subsets identified as TSPs candidates in the bone marrow or blood and the progenitors subsets identified in the thymus with their corresponding flow ...

Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Thus, there is an urgent need for advanced therapies for patients suffering from severe and refractory autoimmune diseases, and researchers have considered cell therapy as potentially curative ...

In vitro, effects of L-arginine on osteoclast differentiation were analysed by RNA-seq and mass spectrometry (MS). Seahorse, Single Cell ENergetIc metabolism by profilIng Translation ... For both, ...