Monocyte subsets were identified according to the CD14 and CD16 expression into classical subpopulation (CD14+16-), intermediate subpopulation (CD14+16+), and non-classical subpopulation (CD14 low 16+ ...

CD14是单核细胞的相对特异性标记物，其中CD14^high CD16^-的人单核细胞被称为经典单核细胞，而CD14^+ CD16^+细胞则为非经典单核细胞。对于小鼠单核细胞，常用的标记物包括CD11b和Ly-6G（Gr-1）。 巨噬细胞广泛存在于多种组织中，依据其所在位置和功能可分为不同类型 ...

The percentage of classical (CD14 high CD16-) monocytes/macrophages demonstrated a steady decrease over time, whereas the proportion of intermediate (CD14 high CD16 +) monocytes/macrophages slowly ...

Aortic dissection (AD) is a serious cardiovascular disease characterized by a tear in the inner layer of the aorta [1, 2]. Consequently, blood flows between the layers of the aortic wall and forces ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

本研究评估了慢性辐射对Techa河流域居民免疫系统的长期影响。结果显示，中等辐射剂量组中CD14⁻CD16⁺单核细胞的比例显著高于对照组，揭示了辐射对免疫调节的潜在机制。 研究团队使用LongCyte®流式细胞仪，结合CD14、CD16和CD45等标记物，精准分析外周血 ...

Specifically, CD62L-CD86 + myeloid dendritic cells and CD86 + myeloid dendritic cells demonstrated protective effects, whereas CD14 + CD16 + monocytes were identified as risk factors. Furthermore, the ...

Blood samples were collected after overnight fasting to analyze monocyte subpopulations using flow cytometry, which identified classical monocytes (CD14+CD16-), intermediate monocytes (CD14+CD16+), ...

另外，HLA DR + NK % NK（HLA - DR 是一种在活化的 NK 细胞表面常见的分子，它与抗原呈递有关 ）和 CD16 在 CD14 - CD16 + 单核细胞上的特征，与子宫性不孕（FIUTERINE）的风险增加有关；而 CD86 + 髓样 DC AC（髓样 DC 细胞是专门的抗原呈递细胞，负责捕捉、处理和呈递抗原给 ...

研究人员开展双向两样本孟德尔随机化（MR）研究，明确免疫细胞特征与结直肠癌（CRC）因果关系，提供新治疗靶点。 结直肠癌（Colorectal Cancer，CRC），这个听起来有些陌生的名字，却是全球范围内严重威胁人类健康的 “杀手”。在美国，它是第三大常见癌症 ...