Inflammatory mediators can act in an autocrine manor, CCL2 and CCL5 for example activate VSMCs to undergo phenotypical changes in ... both innate and adaptive immune cells such as activated T cells ...

Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...