Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Various immune cells are involved, and as one of the key immune cells residing in the heart, macrophages play an indispensable role in the inflammatory and reparative processes during cardiac ischemia ...

Both liver-resident macrophages (Kupffer cells) and monocyte-derived macrophages are important drivers of fibrosis progression, but can also induce its regression once triggers of chronic inflammation ...

为探究多发性骨髓瘤骨病（MBD）发病机制，研究人员研究补体 C3a 与 Sirt1 关系，发现 C3a 激活破骨细胞机制，或为 MBD 治疗提供新靶点。 在血液系统疾病的研究领域中，多发性骨髓瘤（Multiple Myeloma，MM）一直是备受关注的焦点。MM 作为一种恶性血液疾病，常常 ...

Males with pulmonary arterial hypertension (PAH) have more proinflammatory macrophages — a type of immune cell — in the lungs than do females with the disease, a study suggests. Researchers identified ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

The manuscript contains important findings regarding inflammatory macrophage subsets that have theoretical and/or practical applications beyond the field of rheumatology. The authors demonstrate with ...

9 These ectosomes express PS and are capable of inducing the release of TGFβ by monocyte-derived macrophages. In vitro, neutrophil-derived ectosomes have been shown to suppress the response to TLR ...

This useful study presents findings on the efficacy and mechanisms of linalool protection against Saprolegnia parasitica oomycetes in the grass carp model. The evidence presented is solid since the ...

Department of Chemistry, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois 60208, United States ...