Spironolactone's safety profile had been primarily generated from trials of older people with heart failure, so its safety in ...

The landmark Randomized Aldactone Evaluation Study (RALES), published in 1999, showed that spironolactone, a potassium-sparing diuretic, improves outcomes in patients with severe heart failure.

Aldactone (spironolactone) is the most commonly used anti-androgen in the United States. It is a type of steroid that not only works as a testosterone blocker but is also used as a diuretic ...

Spironolactone oral tablet is a generic drug prescribed for heart failure, high blood pressure, and other conditions in adults. It is available as the brand-name drug Aldactone. An interaction ...

Objectives: This study was designed to investigate the appropriateness and complications of the use of spironolactone for heart failure (HF) in clinical practice. Background: Spironolactone was ...