Purpose: The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. Summary: Five randomized, placebo-controlled trials involving quetiapine as monotherapy or ...

The Cleveland Clinic explains that mania is part of bipolar disorder. It says: "Acute mania is the manic phase of bipolar I disorder. It is defined as an extremely unstable euphoric or irritable ...

If someone is experiencing an acute manic episode, meaning they are actively in the middle of one, treatment typically begins with mood stabilizers. These first-line treatments include medications ...

Interestingly, the first English language report on the use of antipsychotic agents in schizophrenia also showed that these drugs have efficacy in the treatment of acute mania, which clinicians ...

This study demonstrated the efficacy of quetiapine as monotherapy for acute mania, though relatively low lithium concentrations may have precluded a qualitative comparison of the two drugs.