Our findings identified three clinically meaningful factors corresponding to 'elated mania',' irritable mania' and 'psychotic mania'. These findings support the multidimensional nature of manic ...

Purpose: The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. Summary: Five randomized, placebo-controlled trials involving quetiapine as monotherapy or ...

Interestingly, the first English language report on the use of antipsychotic agents in schizophrenia also showed that these drugs have efficacy in the treatment of acute mania, which clinicians ...

The Cleveland Clinic explains that mania is part of bipolar disorder. It says: "Acute mania is the manic phase of bipolar I disorder. It is defined as an extremely unstable euphoric or irritable ...

The protein kinase C (PKC) signaling cascade has been identified as a direct biochemical target for the treatment of mania. Preclinical studies and early clinical trials have shown that the ...