In addition to 2′3′cGAMP, small molecule 5,6-dimethylxanthenone-4-acetic acid (DMXAA) or cyclic dinucleotides (CDNs) of prokaryotic origin, such as c-di-AMP, c-di-GMP, and 3′3′cGAMP (canonical), are ...

The direct enzymatic conversion of an amino acid side chain to a chemical reporter ... Even subtle perturbations to the structure of a protein, glycan or lipid may affect its biological activity ...

For each polysaccharide, we will 1 discuss the structure of the active compound and its efficiency in atherosclerotic plaque reduction, if known. In addition, we will examine the potential for the ...