In contrast, since disseminated intravascular coagulation (DIC) is far less frequent in patients with non-APL acute myeloid leukemia (AML), the pathophysiology of AML-associated hemorrhagic disorders ...

For instance, the majority of patients with sporadic amyotrophic lateral sclerosis (up to 97%) and a substantial proportion of patients with frontotemporal lobar degeneration (~45%) exhibit TDP-43 ...

As you age, your risk for higher blood sugar increases—which raises the risk of type 2 diabetes for adults in their 50s, 60s, and 70s. Using a chart of blood sugar levels by age can help you track ...

Revumenib was added to the latest NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines ®) for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) as a category 2A ...

Despite its physiological function, dysregulation of the R-loop leads to DNA replication stress and excessive inflammation and is associated with AML pathophysiology. Mutations of cellular RNA-binding ...

Legal drafters, policy makers, financial sector AML/CFT supervisors, supervisors of designated non-financial businesses and professions, financial intelligence unit officials, criminal justice ...

December 14th 2023Access Considerations for Gene Therapies Among Patients With Rare Diseases ...

The Securities and Commodities Authority (SCA) has imposed stringent financial penalties on several companies for violating regulations and failing to comply with anti-money laundering and counter ...

Its latest findings highlight gaps in effectiveness across areas like risk-based approaches, enforcement and information sharing. The changes in legislation mean AML compliance processes must be more ...

The FDA granted fast track designation to AUTX-703 for the treatment of patients with relapsed/refractory acute myelogenous leukemia (R/R AML). Preclinical studies demonstrated dose-dependent survival ...