Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce the risk of cardiovascular death or worsening heart failure (HF) in outpatients with HF. Data are limited regarding initiation in ...

Background: Artificial intelligence (AI)-enhanced electrocardiogram (ECG) models are often designed to detect specific anatomical and functional cardiac abnormalities. Understanding the selectivity of ...

Background: In addition to the risk of stroke, patients undergoing transcatheter aortic valve implantation (TAVI) are susceptible to a decline in neurocognitive function. This may occur due to ...

You may have been tested for the condition known as factor V Leiden (pronounced factor five lye / -den) because you or someone in your family has had a blood clot in one of the deep veins of the body ...

When a blood clot forms in the deep veins of the body, it is called deep vein thrombosis (DVT). DVT occurs most commonly in the leg; however, it can occur anywhere in the body, such as the veins in ...

Explore the latest research and articles on cardiovascular health and disease in Circulation's current issue.

About JAHA Mission Statement: The Journal of the American Heart Association (JAHA): Cardiovascular and Cerebrovascular Disease is an international, peer-reviewed, open access, scientific journal that ...

To examine the provenance of these recommendations, we briefly review the clinical trial history of hydrochlorothiazide and chlorthalidone. MRFIT (Multiple Risk Factor Intervention Trial) used a ...

Background: Transcatheter aortic valve replacement (TAVR) is increasingly performed in younger, low surgical risk patients. This NOTION-2 study reports mid-term outcomes in low-risk patients aged ...

Electrolyte abnormalities are commonly associated with cardiovascular emergencies. These abnormalities may cause or contribute to cardiac arrest and may hinder resuscitative efforts. In some cases ...

Left ventricular ejection fraction (LVEF) 1 has persisted as the primary measure of left ventricular systolic function despite flaws in this approach. Patients with heart failure are relieved when the ...

Abstracts from American Heart Association's Epidemiology and Prevention/Lifestyle and Cardiometabolic Health 2025 Scientific Sessions Volume 151 Number Suppl 1 March 11, 2025 ...