Sejnowski, also at the Salk Institute, to focus on the role of methylation in the brain. To pinpoint the location of methyl groups, Ecker and his colleagues process DNA in a way that converts every ...

In RNA, a point mutation can involve the substitution of uracil with another nucleobase, such as cytosine (C) or guanine (G). These mutations can potentially alter the amino acid sequence of the ...

Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...

In 1992, researchers found that the amination reaction of sodium bisulfite with unmethylated cytosine is different than the reaction of sodium bisulfite with 5mC. Because of this difference, ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Nucleotides are the combination of a five-carbon sugar, ribose, along with a phosphate group and one of five possible ...

In addition to the five nitrogenous bases—adenine, guanine, cytosine, thymine and uracil—required for building DNA and RNA, the researchers also found xanthine, hypoxanthine, and nicotinic ...

The decoding of information in a cell's DNA into proteins begins with a complex interaction of nucleic acids. Learn how this step inside the nucleus leads to protein synthesis in the cytoplasm.