From the approval of the first immune checkpoint inhibitors to the development of chimeric antigen receptor T cells, immunotherapy has demonstrated ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer ...

However, 25-hydroxycholesterol prevents this inhibition, and therefore enables better activation of anti-tumor immunity. Prof. Hugues' team then deleted this enzyme in mouse lymphatic endothelial ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune ...

Additional Phase 2 data for vilastobart,a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab in patients with MSS CRC ...

“Trained innate immunity (TRIM) has emerged as a major immunological principle that challenges ... “So, although TRIM can ...