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Figure 1: The tubulin–colchicine:RB3-SLD complex. A comparison of the structure of tubulin heterodimers in T2R (which is similar to that of GDP–tubulin in curved protofilaments 11) and in ...
The C-terminal domain of GCP4 binds directly to γ-tubulin. Structure-based sequence analysis also revealed the existence of an exposed surface area conserved in all hGCPs and in GCP4 orthologs.
As well as serving an essential role in the structure and basic operation of cells, tubulin has also been identified as a potential novel therapeutic approach for cancer treatment. Microtubules ...
This study newly identified the PSD lattice backbone structure and provides a new PSD architecture model comprising a non-microtubule tubulin-based backbone structure and its associated proteins ...
Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help ...
Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help ...
The pattern of these markers makes up the "tubulin code" and according to a paper published in Cell, ... California, have revealed the 3-D structure of TTLL7 bound to the microtubule.
“It had been proposed that tubulin had to be constrained, but no one had proved it,” Nogales said. “What we have seen is that as GTP hydrolysis happens, the tubulin structure gets stuck in a strained ...
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