Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get them moving again. Shelby is an assistant editor for The Scientist. She ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...

However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...

This research thoroughly elucidates the dynamic multi-conformational characteristics of ribosomes during the translation process. "Understanding the entire translation process in depth helps us ...