The mean spironolactone dose was 26 mg/day. The results demonstrated a 30 ... which was significantly greater in male patients taking spironolactone (10%) than men in the placebo group (1%).

However, they might recommend starting with 25 mg a day and slowly increasing your dose to reduce your risk of side effects. Spironolactone sometimes causes drowsiness, so it’s best to take it ...

The following is a summary of “Sodium Zirconium Cyclosilicate for Management of Hyperkalemia During Spironolactone ...

Among 203 patients, 71% of those taking SZC achieved the primary endpoint of optimal response -- normokalemia while on at least a 25-mg dose of spironolactone ... (one and 10 events, respectively ...

25–50 mg daily for 1 year. Five patients taking spironolactone and one patient on placebo developed hyperkalemia within 2–12 weeks of initiation of study medication and were excluded.