SIM typically provides a resolution improvement of about 2-fold compared to conventional microscopy. While SIM offers faster imaging speeds and lower phototoxicity compared to STED, its resolution ...

This is especially true when studying intricate details beyond the optical resolution limit using structured illumination ...

The inverted Nikon N-SIM/A1 microscope is a combination structured illumination microscopy (SIM), laser scanning confocal and total internal reflection fluorescence (TIRF) microscopy system. SIM and ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

The Olympus FluoView FV1000 Confocal Microscope is a laser scanning biological microscope ... It features simultaneous application of two laser scanners (SIM or SIMultaneous scanner) to enable ...

This is the intrinsic limitation on a microscope's ability to focus on objects smaller than the wavelength of light being used. Structured illumination microscopy is one of the super-resolution ...