City Hope Cafe operates a free cafe and a sense of normalcy in the heart of a troubled inner-city neighborhood.

New chief medical officer at longtime homeless nonprofit says there's no silver bullet for a "multi-factoral" problem.

The City of San Francisco is providing free beer and ... Disorder)," Nathan wrote on X after visiting the hotel in Tenderloin ...

The police department released footage from the standoff with the suspect of last week's shooting of a tenderloin shopkeeper.

In his inaugural speech, new San Francisco ... "Help us with the Tenderloin, because a lot of kids, like my daughter, walk into the street. And there's a lot of people, homeless, and drugs in ...

In San Francisco, an approach that gifts cellphones to homeless people – with someone on the other end – helps to forge human ...

A Trump promise could be ‘catastrophic’ to California’s wine industry,” a Nov. 13San Francisco Chronicle headline read. “Farm ranchers in my district already have tro ...

Firefighters in San Francisco on Sunday night knocked down a fire in a top-floor apartment in the Tenderloin that displaced eight people, the department said. The one-alarm fire at 201 Leavenworth ...

SAN FRANCISCO — Four hours ... through the bleak confines of the Tenderloin district with the city police chief and passing out coffee to people at a homeless community center.