Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...
The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a ...
The specific structure of a protein determines its unique biological function. (click on image to enlarge) (Image: National Human Genom Research Institute) Proteins are built from a set of 20 standard ...
Evolution has been fine-tuning life at the molecular level for billions of years. Proteins, the fundamental building blocks of life, have evolved through this process to perform various biological ...
These bonds are dynamic, rapidly forming and breaking over time as the protein folds. Because it only takes nanoseconds to microseconds for a protein to morph along its path to its final structure, ...
In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...
The recent study focused on the viral polymerase complex, a crucial set of proteins the virus ... component of the virus functions. Understanding the structure and behavior of the polymerase ...