Although early indications suggest that these new therapeutics are well tolerated, stimulation of c-Mpl may potentiate platelet activation and trigger thrombosis, a particular concern for older ...

These T cells then activate platelets in the spleen; platelets are the cell fragments that set off blood clot formation. Upon re-entering circulation, the primed platelets are better able to ...

The same platelet RNA molecules - signs of megakaryocyte activation - were associated with longer-lasting antibody production for the various vaccines. The molecular signature could predict which ...