X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

The disease seems to occur in one of two patterns ... right infraorbital fissure, right maxillary bone, lacrimal bone, malar process and zygomatic bone. These bones were soft, suggesting that ...

Genetic studies in patients with apparent sporadic Paget disease are difficult to interpret because this disorder is often asymptomatic. Bone scans of a patient's parents are required to rule out ...

A young woman from Los Angeles suffered intense pain in her leg to the point she could not walk before being diagnosed with a ...

This World Cancer Day, we've put together everything you need to know about bone cancer – and how to look spot the symptoms.

Osteoporosis is common in older adults, especially females and happens due to loss of bone mineral density. Whereas, Paget disease involves thickened and weaker-than-normal bone. The cause is not ...

Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early research shows that taking ipriflavone might decrease bone pain in some ...