Fibrates are widely prescribed agonists of transcription factor peroxisome proliferator-activated receptor (PPAR)-α, and are used to treat patients with atherogenic dyslipidemia. These drugs ...

In light of the poor performance and late-stage failures of some drugs targeting PPARs, Gromo says it is important to recognize that all PPAR agonists are unique, and each has different benefits ...

Ipsen has taken rights to PPAR agonist elafibranor as a treatment for primary biliary cholangitis – a chronic, autoimmune disease in which bile ducts in the liver are gradually destroyed causing ...

Delta4 receives European patents for two compounds as candidate treatments for focal segmental glomerulosclerosis: Vienna, Austria Monday, February 3, 2025, 18:00 Hrs [IST] Delta4 ...

Treatment of patients with active ulcerative colitis with a PPAR-γ agonist, rosiglitazone, significantly reduced the ulcerative colitis disease activity index score and resulted in an improved ...