Bone remodelling takes place in specialized modelling units spread throughout the skeleton and involves bone resorption by mature osteoclasts, followed by differentiation of osteoblast precursors to ...

What determines the switch from bone formation to resorption has been unclear. Researchers show that intercellular communication via extracellular vesicles from bone-making osteoblasts is a key factor ...

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

Osaka, Japan – Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Researchers at UC San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue — by feeding them adenosine, a naturally occurring molecule in the ...

Researchers from Osaka University have identified a gene underlying the development of osteoporosis and developed a new mouse model, pointing the way for future treatments and a greater understanding ...