To the Editor: NMR spectroscopy is currently the only technique for determining the solution structure of biological macromolecules. This typically requires both the assignment of resonances and a ...

With a new method for optimizing the amino acid isotopic labeling pattern, stereo-array isotope labeling (SAIL), structures of large proteins (up to 50 kDa) can now be solved with ease with ...

Nearly every element has at least one isotope that is NMR active. Since then, NMR spectroscopy has become an indespensible tool for the determination of molecular structure, the study of molecular ...