Repeated brain injury resulted in SOD1-ALS mice showing greater weight loss, an earlier tremor in the hind limbs, and ...

A gene-edited mouse with two male parents has survived to adulthood, pushing new progress on stem cell research.

The mouse model closely mimics the specific dysferlin mutation and resulting disease, and enabled the researchers to evaluate how the complete therapy works—taking muscle stem cells, correcting ...

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse ...

A team of researchers has successfully engineered a bi-paternal mouse - a mouse with two dads - that survived until adulthood ...

"Although mutations in the envelope proteins contribute to the adaptation, they are not solely responsible for the phenotype." The virus' adaptation to mouse cells, which has been demonstrated ...

2012;7(1):81-92. Homozygous R132H/R132H mice showed no serious overt phenotype, [49] which contrasts the symptoms of a patient with the corresponding mutation. However, the mice did show impaired ...

"The mutation-containing HSCs give rise to proinflammatory ... to the bad proteins that hurt normal cells." The LJI team used mouse models with mutated ASXL1 to solve this mystery.

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...

SIL-204 administered in an extended release formulation reduced tumor growth by ~50% after 30 days, with ~50% of tumors showing complete necrosis, in human pancreatic tumors harboring a G12D mutation ...