Possible candidates for the protein that constitutes the mPTP include the voltage-dependent anion channel, adenine nucleotide transporter and the mitochondrial phosphate translocator protein.

We have also recently demonstrated that the adenosine nucleotide translocase (ANT) proteins are integral components of the mitochondrial permeability transition pore (MPTP). We have found that ...

Due to their similarities to bacteria, mitochondria can actually trigger severe illness in humans. How can organelles inside our bodies suddenly become a threat? What evidence did Margulis use to ...

For instance, inhibitors of MCU and stabilizers of mitochondrial permeability transition pore (mPTP) show promise in preclinical models. In this review, we emphasize the role of Ca2+mito in both ...

Protective role of mitochondrial protein Mitofusin 2 in cellular health revealed Date: February 14, 2025 Source: University of Cologne Summary: A research collaboration has found that besides ...