Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...

Researchers warn that this finding does not imply that cancer patients can take aspirin without a medical prescription.

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple ...

Immunodeficient mouse holding human tumor cells and human immune cells demonstrates tumor metastasis in the lungs. Such tumor metastasis is prevented by short synthetic mRNA injections, as they ...

Breast cancer and many other types of cancer metastasize to the lungs. In research involving three mouse models of metastatic ...

Hypoxia enhances proliferation, angiogenesis, metastasis, chemoresistance, and radioresistance of HCC; suppresses differentiation and apoptosis of HCC; and consequently leads to tumor malignancy.

In particular, they found that mice lacking a gene that produces a protein called ARHGEF1 had fewer metastases of various primary cancers to the lungs and liver. The researchers determined that ...