Hosted on MSN3mon
Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
ALL affects the immature forms of white blood cells, called lymphocytes and has two types: B-ALL and T-ALL, named for whether B-lymphocytes or T-lymphocytes are affected. Historically, children ...
Nature6mon
Gene expression analysis of glucocorticoid-induced apoptosis by a gene microarray technique
Glucocorticosteroids induce apoptosis in immature lymphocytes and are therefore commonly used to treat patients who have lymphoid leukemia or lymphoma. To understand the genetic pathways and ...
Nature5y
Damage limitation
...ATM has a crucial role in maintaining genomic stability by activating cell-cycle checkpoints in response to DNA damage. During their development, all lymphocytes undergo a potentially dangerous ...