Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and inflammation associated with acute gout. As demonstrated in a novel mouse model ...
and severe pain, usually in one joint. The most common place for gout is the base of the big toe, but it can happen in other joints such as the elbow, knee, wrist, ankle, and instep. If your ...