The final section of the book provides current overviews of the replication of medically important DNA viruses. As for cellular DNA replication, significant advances in our understanding of how ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

View Full Profile. Learn about our Editorial Policies. Using a technique called “DNA origami,” researchers created traps that encase large viruses—such as SARS-CoV-2, influenza A, and Zika—in hopes of ...

With only seven genes, the BK polyomavirus must use the host cell's DNA replication machinery to produce new viruses. Although the virus was discovered over 50 years ago, little is known about how ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

1 To adapt this technology for diagnostics, the team developed a one-pot approach that starts with the enzyme ribonuclease H, guided by DNA oligos, to selectively cut short sections of RNA that ...

These analogs can interfere with DNA replication and induce cell death in rapidly dividing cancer cells or inhibit viral replication. Examples include: 5-Fluorouracil (5-FU): A pyrimidine analog used ...

Researchers studying ancient Neanderthal DNA found traces of three viruses that cause colds, cold sores, genital warts, and cancer. And ancient humans might have been the ones who started ...

Viral reverse transcriptase (RT) plays a critical role in replication (e.g., retroviruses, that reverse transcribe RNA templates into complementary DNA) and genome mutations (e.g., diversity ...

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible ...