A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

A Loganville man was convicted in the 1990 rape and killing of two siblings in Stone Mountain after DNA finally linked him to the crime.

Russell and Shirley Dermond were killed in what an FBI agent called ‘one of the strangest cases I’ve ever seen.’ ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells. Yet, there wasn ...

Despite often being overlooked, Rosalind Franklin's contribution to the understanding of molecules was vital. Read on to find ...

The authors have demonstrated the use of adenine base editors delivered via adeno-associated viruses to introduce edits in the mitochondrial genome. The manuscript describes the methodology well, and ...