A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Russell and Shirley Dermond were killed in what an FBI agent called ‘one of the strangest cases I’ve ever seen.’ ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

A Loganville man was convicted in the 1990 rape and killing of two siblings in Stone Mountain after DNA finally linked him to the crime.

The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells. Yet, there wasn ...