Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues. However, a ...

[1,2] Collagen diseases affect women and men differently ( Table I). For example, SLE affects primarily women, and the predilection of the disease for young women of childbearing age suggests that ...

A groundbreaking study by researchers at Rice University and the University of Virginia has revealed unexpected structural ...

Dermatomyositis is a rare disease of presumed autoimmune etiology with skeletal muscle damage by a predominantly inflammatory lymphocytic infiltration, accompanied by characteristic skin changes.

The presence of cutaneous changes in systemic diseases has been particularly emphasized in recent years with the discovery of new findings in collagen diseases. The work of Libman and Sacks ...

The mechanism for breakdown of collagen is unknown, and to date a collagenase has not been demonstrated in man. The elevated excretion of hydroxyproline in Paget's disease, hyperparathyroidism and ...

they only slow disease progression, and are costly and associated with adverse effects. Khan et al. screen a library of 712 FDA-approved drugs for inhibitors of ECM-deposited collagen in cultured ...

Stuart Therapeutics completed a Phase 3 trial for ST-100, a treatment for dry eye disease, involving a randomized, ...

The result of their efforts is "sicXer," a so called "mesoporous silica-collagen xerogel" engineered ... may have applications in non-malignant diseases involving bone degeneration or fractures.