In a study of mouse and human genes, scientists pinpointed 145 genes that regulate the cartilage cells in kid's growth plates and could determine how tall they grow. When you purchase through links on ...
In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers at the University of Basel have now discovered that these skeletal cells do not just ...
Nearly a quarter of the U.S. population has some form of arthritis, most frequently osteoarthritis—a type of degenerative joint disease that wears down cartilage at the ends of bones, making it ...
SMART researchers have developed a new method to assess the potential of mesenchymal stromal cells (MSCs) to repair cartilage. This method is faster (9 days) compared to the current standard (21 days) ...
Osteoarthritis is a progressive disease where the protective layer of articular cartilage that cushions the junctional surface of bones in joints degenerates. This restricts movement and causes ...
Researchers have found that osteoarthritis in mice is caused by the depletion of specialized gene-expressing cartilage-forming stem cells and found a way to reverse the condition. The discovery opens ...
Using a new fluorescent mouse model with advanced imaging techniques, researchers have successfully visualized how musculoskeletal components are integrated into the functional locomotor system during ...
Scientists at The Scripps Research Institute (TSRI) report why the risk of osteoarthritis (OA) increases as we age. They also describe a new approach for developing new therapies to maintain healthy ...
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found. The treatment ...
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Early bone molecular changes signal osteoarthritis progression
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease ...
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