Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...

To illustrate the feasibility of targeted sequencing in conjunction with CRISPR screens, a single-cell RNA sequencing experiment was conducted using a WTA approach. Here, all expressed genes are ...

The idea behind the notorious CRISPR-baby scandal, editing reproductive cells or embryos tinkers with DNA ... Doctors already use technologies that screen people’s genes to monitor for breast cancer, ...

Schmid Burgk and first author of the paper. "For a conventional CRISPR screen, it often takes months to precisely separate the cells according to their function." Another advantage of the new ...